Table 1: Antiviral effect of Stalosan F on AIV Concentration Exposure of Stalosan time 10 mg 20 mg 5 min 10 min 1 h 6 h 5 min 10 min 1 h 6 h Treatment Control Treatment Control Treatment Control Treatment Control Treatment Control Treatment Control Treatment Control Treatment Control R1 <0.5 4.17 <0.5 4.83 <0.5 4.17 <0.5 3.17 <0.5 4.5 <0.5 4.83 <0.5 4.5 <0.5 3.83 R2 <0.5 4.83 <0.5 4.5 <0.5 4.83 <0.5 2.83 <0.5 5.17 <0.5 4.5 <0.5 4.5 <0.5 3.5 R3 Average <0.5 0.50 4.5 4.50 <0.5 0.50 4.83 4.72 <0.5 0.50 4.5 4.50 <0.5 0.50 3.17 3.06 <0.5 0.50 4.5 4.72 <0.5 0.50 4.5 4.61 <0.5 0.50 4.5 4.50 <0.5 0.50 2.83 3.39 SD % of reduction 0.000 0.330 0.000 0.191 0.000 0.330 0.000 0.196 0.000 0.387 0.000 0.191 0.000 0.000 0.000 0.510 >99.990 >99.994 >99.990 >99.722 >99.994 >99.992 >99.990 >99.870 Conclusions: Greater than 4 log 10 of AIV was inactivated by both 10 mg and 20 mg of Stalosan F within 5 minutes. 3
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