Page 2 of 2 3 Study Number 16452 STATEMENT OF NO DATA CONFIDENTIALITY CLAIMS No claim of confidentiality is made for any information contained in this study on the basis of its falling within the scope of FIFRA 10 (d) (1) (A), (B) or (C). Company: ARCH ANGEL LLC Company Agent: Name Title Signature Date
Page 5 of 2 3 Study Number 16452 TABLE OF CONTENTS STATEMENT OF NO DATA CONFIDENTIALITY CLAIMS .2 GOOD LABORATORY PRACTICE STATEMENT .3 QUALITY ASSURANCE STATEMENT .4 TABLE OF CONTENTS .5 DERMAL SENSITIZATION STUDY IN GUINEA PIGS (BUEHLER METHOD) .6 1. PURPOSE . 6 2. SUMMARY . 6 3. MATERIALS . 7 4. METHODS. 8 5. PROCEDURE. 9 6. EVALUATION . 10 7. HISTORICAL POSITIVE CONTROL VALIDATION STUDY . 11 8. STUDY CONDUCT. 11 9. REFERENCES . 11 10. QUALITY ASSURANCE . 11 11. DEVIATIONS FROM FINAL PROTOCOL . 12 12. FINAL REPORT AND RECORDS TO BE MAINTAINED. 12 13. RESULTS . 12 14. CONCLUSION. 13 SIGNATURES .14 TABLE 1: PRELIMINARY IRRITATION TESTING SCORES FOR DETERMINATION OF HNIC .15 TABLE 2: INDIVIDUAL BODY WEIGHTS (TEST SUBSTANCE).16 TABLE 3: INDIVIDUAL BODY WEIGHTS (POSITIVE CONTROL).18 TABLE 4: INDUCTION PHASE SKIN REACTION SCORES (TEST SUBSTANCE) .19 TABLE 5: INDUCTION PHASE SKIN REACTION SCORES (POSITIVE CONTROL) .20 TABLE 6: CHALLENGE PHASE SKIN REACTION SCORES (TEST SUBSTANCE).21 TABLE 7: CHALLENGE PHASE SKIN REACTION SCORES (POSITIVE CONTROL).23