3. Radiotherapy with a MR-linear accelerator: OUH has invested in a MR-accelerator, combining a linear accelerator with a 1.5 T MR-scanner which will be ready for treatment of patients late in 2018. With a MR-accelerator it is possible to achieve an image quality which is comparable with images from a diagnostic MR-scanner. With MR-images before and during the radiation treatment, the geometric uncertainty of the radiation field can be reduced. This allows a reduction of the irradiated volume and thereby a reduction of the side effects of the radiation treatment. During the past years, the development of radiation biomarkers from Cone Beam CTimages has been an active area of research in the Department of Oncology. Compared with these, MR-images contain much more physiological information allowing an increase in sensitivity and specificity of such biomarkers which hopefully translates into improved clinical results for the patients. Daily MR-images during radiation treatment will enable studies of early changes in tumour as well as normal tissue. Our aim is to be able to predict the radiation sensitivity early in the treatment course. Today large groups of patients are treated similarly due to lack of knowledge of radiation sensitivity. With knowledge of the individual radiation sensitivity we can optimize treatment with the highest possible dose to the tumour with the lowest possible likelihood of side effects. Such tailored radiotherapy is equivalent to precision medicine within medical cancer treatment. 4. Research into elderly cancer patients: AgeCare is an elite research centre embedded in the Department of Oncology. It is a 5-year research grant from 2014 to 2018 with the potential for a 5-year extension from 2019 to 2023. The research is divided into 7 work packages, including epidemiology, biomarkers surgery, radiotherapy, medical cancer treatment, and supportive care. For more details, the reader is kindly referred to the AgeCare homepage: http://agecare.org .
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